Nutrifill shortage

Nutrifill is unfortunately unavailable at present. This article is about what you can use instead.

Updated on
Nutrifill shortage

Temporary shortage

Last updated: 3/26/2025

Nutrifill is temporarily unavailable. At this time, the manufacturer does not yet have an estimated back-in-stock date. 

Nutrifill is a special product that is very important to a lot of us, particularly those with very dry eyes, very diseased corneas, or very sensitive eyes (or all of the above). I know some of you have already tried everything else. It's always a bit unsettling when a product we rely on for our scleral lenses becomes unavailable. But, we can always make it through, though it may mean some adjustments to our routines!

Talk to your provider

If Nutrifill is your normal filling solution, make sure to let your provider know if you're not able to get more and ask for their guidance on substitutions.

Alternative filling solution options

Buffered salines (ScleralFil, Purilens)

Scleralfil

The obvious "most similar" choice is Scleralfil

What's the same:

  • Type (buffered - pH balanced to match the eye)
  • Size (10mL vial)

What's different:

  • Cheaper
  • Sold in box of 30 (vs Nutrifill which is 35)
  • Buffering system: Both products are buffered, meaning they have additives to raise and stabilize the pH. Nutrifill is phosphate-buffered, while Scleralfil is borate-buffered.  
  • Ingredients: Other than sodium chloride (salt) and water, Nutrifill contains alcium, magnesium potassium and phosphate, while Scleralfil contains sodium borate and boric acid. These ingredients are also common in artificial tear products.

Purilens

Purilens has the same ingredients as Scleralfil but is packaged differently. It is sold in 2oz and 4oz sizes. The bottles are the "puncture" type, and the bottles must be discarded either within 14 days (per label) or earlier, depending on your doctor's advice. Some prefer their patients not to fill sclerals with Purilens more than 48 hours after the bottle is open, due to potential for contamination. it is a very popular solution for rinsing, however, especially for newer "high utilization" scleral users. 

2oz size is sold in 2packs and 6packs)

4oz size is sold in 3packs, 6packs and 12packs

Click on Purilens to browse all.

Unbuffered salines + PF tears

If you are used to buffered saline, then unbuffered saline (which is acidic) may not be comfortable for you. However, some people with sensitive eyes may not be able to tolerate the borate-buffered salines (Scleralfil and Purilens). In this case, an alternative that has long been popular is to use an unbuffered saline e.g. Lacripure, VibrantVue or Tangible Fill but add one or more drops of a preservative-free artificial tear. Refresh Celluvisc is common as a supplemental filling solution (our last poll indicated that 61% of those who add something to saline are adding Celluvisc).

Fill with PF tears only

Expensive, and only suitable for some users, but definitely an option. Check with your provider.

Economical options for trying different salines

We know it's frustrating to have to buy a full box of a product only to find that it doesn't agree with you. Here are the smallest quantities available of each:

In terms of artificial tears used for filling, the cheapest preservative-free brand name option that I know of us Refresh Plus 70packs sold at Costco.

Community sharing?

Please post in the comments if you have an urgent need or if you have extra to share.

If you have a severe eye condition, are dependent on Nutrifill, and do not have enough to last, please feel free to post in the comments here in case we can help.

If you have any unopened boxes of Nutrifill sitting on your shelf that you can spare, please post in the comments or let us know. 

We'll work to facilitate getting extras from givers to givees by providing shipping labels (either direct, for those that are agreeable, or coming to us and then getting sent out).

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8 comments

I’m a post-keratoconus, multiple corneal transplant patient who’s still recovering from recent graft rejection in both eyes. I live in CO, where the dry climate exacerbates general ocular surface keratitis/didease, but cell loss & other complications following the rejection has made the discomfort insufferable & I’ve been unable to tolerate my sclerals at all (& since I’m legally blind wo them & can’t see w glasses, it’s been an adventure!). Not the time for Nutrifill to lose their supply chain! Best alternative I’ve found so far is prob Refresh Plus PF (mixed w custom serum tears), but it’s not great. All the others on my optho’s list cause stinging & cloud my vision almost immediately. Has anyone tried Tangible Fill? Or had any luck mixing some kind of saline cocktail dupe for Nutrifill? If so, please let me know – and/or if anyone can spare some Nutrifill, my eyes & I would be so-o grateful!

Amy P.

I am down to my last vials of Nutrifill. Obviously I would love to purchase some if anyone had any extra they could spare.

Thanks in advance. Thanks for facilitating this. :)

Blake Nieman-Davis

I have severe dry eye with peripheral ulcerative keratitis and sensitive eyes. I have only used Nutrifill with PROSE lenses. 😔

Lesley Ellis

Out of Nutrifill. Tr led others with not good results. Would.love to buy a box.

Tamra Lyman

I have 2 unopened boxes of Nurtifill and also a partial box if anyone needs.

Lora Thompson

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