We ship Mon-Fri. Orders ship same day if placed by cutoff (1:30pm Pacific Time). (Exception: Purilens). 
Urgent order? Call 877-693-7939 or click here to understand your options.

On Sale

SKU: ALL 95773

Refresh Optive MEGA-3 (30 PF vials)

Rated 4.4 out of 5
Based on 18 reviews
Sale price

  • - $-21.75
  • Regular price $21.75
    ( / )
    Purchase Options
    Delivery Frequency

    About Refresh Optive MEGA-3

    • Active ingredients: Carboxymethylcellulose, glycerin, polysorbate 80
    • Also contains castor oil and flaxseed oil
    • Preservative-free
    • Box of 30 0.4mL vials

    Description (by Rebecca)

    This is the latest in the Refresh - slash - Optive branded line. First we had Optive (actives: glycerin and carboxymethylcellulose), then Optive Advanced (those, plus polysorbate 80), and now Optive MEGA-3 (all of the above plus flaxseed and castor oils, tucked quietly into the inactive ingredients list like all lipids. I will leave all discussion of fancy schmancy ingredients like trehalose to the manufacturer (below).

    The trend in artificial tears in general for several years now has been to offer a variant with a lipid, now that the dry eye world is gradually becoming so much more meibomian gland savvy. I must say, Dr Holly was way, way ahead of that trend, with FreshKote (which I was using, albeit under a different name, more than 15 years ago). And some of you will remember Refresh Endura which had castor oil but was discontinued some years back. Then came Soothe XP, Systane Balance, Retaine MGD and so on. 

    Refresh Optive MEGA-3 is quite new and I've had very little feedback on it though I'm quite prepared for the usual I-love-it and I-hate-it. Bottom line is, if you need to try something new and want something with lipids, might be worth a whirl.

    It's rather amusing to me that the manufacturer takes a dig at Retaine MGD in their description. If someone finds a drop that works for them, are they actually going to care that they have to waste a millisecond shaking the tube before opening it? Ah well.

    Description (from the manufacturer's literature)

    Our most advanced formula – REFRESH OPTIVE® Mega-3.

    • Preservative-free, low blur formula fortifies and restores the lipid layer. Its unique blend of natural oils helps prevent tear evaporation.
    • Treats Dry Eye signs and symptoms associated with Meibomian Gland Dysfunction (MGD).
    • Nourishes all three layers of the tear film damaged by Dry Eye for immediate, long-lasting relief.

    This lipid-enhanced lubricant eye drop is clinically proven to treat the signs and symptoms of Dry Eye. Mega-3 does not require shaking prior to use, unlike Retaine® MGD.

    REFRESH OPTIVE® Mega-3 Preservative-Free Lubricant Eye Drops come in sterile, single-use vials you can take with you anywhere and are safe to use as often as needed.

    • It is the only artificial tear that delivers a blend of flaxseed and castor oils to the tear film, in a stable nano-emulsion formula.
    • Nano-emulsion technology delivers flaxseed and castor oil, fortifying the lipid layer and helping prevent tear evaporation without compromising patient comfort.
    • Polysorbate 80 keeps the nano-emulsion from separating, providing consistent stability—no shaking required.
    • CMC, a water-loving polymer, binds to epithelial cellsto maintain moisture on the ocular surface for rapid on-eye comfort and long-lasting relief.

    All OPTIVE® formulas include the patented osmoprotectant property that comes from the three compatible solutes—glycerin, l-carnitine and erythritol—all of which deliver added protection to the corneal epithelial cells against hypertonic stress.

    MEGA-3 contains a fourth osmoprotectant, trehalose, for an advanced approach to treating Dry Eye symptoms. 

    Drug Facts (from manufacturer's site):

    Active Ingredients


    Carboxymethylcellulose sodium 0.5% (eye lubricant)
    Glycerin 1% (eye lubricant)
    Polysorbate 80 0.5% (eye lubricant)

    Uses

    • For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun.
    • May be used as a protectant against further irritation.

    Warnings 

    For external use only.

    • To avoid contamination, do not touch tip of container to any surface. Do not reuse. Once opened, discard.
    • Do not touch unit-dose tip to eye. 
    • If solution changes color, do not use.

    Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours.


    Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

    Directions

    To open, TWIST AND PULL TAB TO REMOVE. Instill 1 or 2 drops in the affected eye(s) as needed and discard container.

    Other Information

    • Use only if single-use container is intact.
    • Use before expiration date marked on container.
    • Store at 59°-86°F (15°-30°C).
    • Store vials in the pouch until use.
    • RETAIN THIS CART FOR FUTURE REFERENCE.

    Inactive Ingredients

    BORIC ACID; BUTYLATED HYDROXYL TOLUENE; CASTOR OIL; ERYTHRITOL; FLAXSEED OIL; LEVOCARNITINE; PEMULEN TR-2; POLYOXYL 40 STEARATE; PURIFIED WATER; TREHALOSE. MAY CONTAIN SODIUM HYDROXIDE AND/OR HYDROCHLORIC ACID TO ADJUST PH.
    average rating 4.4 out of 5
    Based on 18 reviews
    • 5 Stars
      13 Reviews
    • 4 Stars
      3 Reviews
    • 3 Stars
      0 Reviews
    • 2 Stars
      0 Reviews
    • 1 Star
      2 Reviews
    89% of reviewers would recommend this product to a friend
    Effectiveness
    Rated 4 out of 5
    Ease of Use
    Rated 4 out of 5
    Value
    Rated 4 out of 5
    18 Reviews
    Reviewed by Sharon Weitz C., from Mexico
    Verified Buyer
    I recommend this product
    Age Range
    61 - 70
    Gender
    Female
    Use scleral lenses or PROSE
    No
    Eye Condition(s)
    • Dry eye disease
    Rated 5 out of 5
    Review posted

    Dry Eye

    Prescribed by my doctor Relieves my dryness

    Loading...
    Effectiveness
    Rated 5 out of 5
    Ease of Use
    Rated 5 out of 5
    Value
    Rated 5 out of 5
    Was this helpful?
    Reviewed by Stephanie, from Canada
    Verified Buyer
    I recommend this product
    Age Range
    31 - 40
    Gender
    Female
    Use scleral lenses or PROSE
    No
    Eye Condition(s)
    • Dry eye disease
    • Blepharitis/MGD
    • Non-closing eyelid(s)
    Systemic diseases/conditions related to eye issues
    • Sjogrens/Lupus/Rheumatoid arthritis
    Rated 5 out of 5
    Review posted

    Looove these

    Over the last 3ish years I've moved from/through Hylo --> Thealoz duo gel singles --> now to Refresh Optive Mega 3 and each has felt like a big step up. I was using Hylo constantly, with Refresh I'm down to 2-3 times a day. I'm grateful to have found them!

    Loading...
    Effectiveness
    Rated 5 out of 5
    Ease of Use
    Rated 5 out of 5
    Value
    Rated 4 out of 5
    Was this helpful?
    Reviewed by Carrie G., from United States
    Verified Buyer
    I recommend this product
    Age Range
    51 - 60
    Use scleral lenses or PROSE
    No
    Eye Condition(s)
    • Dry eye disease
    • Blepharitis/MGD
    Rated 5 out of 5
    Review posted

    I like these a lot in my drop rotation!

    These work reliably well for me and I like them a lot. Not too thick, I hate when I can't see after using a drop so I like these. They work well.

    Loading...
    Effectiveness
    Rated 4 out of 5
    Ease of Use
    Rated 5 out of 5
    Value
    Rated 4 out of 5
    Was this helpful?
    Reviewed by Rebecca P., from United States
    Verified Reviewer
    I recommend this product
    Age Range
    71 - 80
    Gender
    Female
    Use scleral lenses or PROSE
    No
    Eye Condition(s)
    • Blepharitis/MGD
    Rated 5 out of 5
    Review posted

    The best I’ve had

    Genuine relief and longer lasting

    Loading...
    Effectiveness
    Rated 5 out of 5
    Ease of Use
    Rated 5 out of 5
    Value
    Rated 5 out of 5
    Was this helpful?
    Reviewed by Judith S., from United States
    Verified Buyer
    I recommend this product
    Age Range
    71 - 80
    Gender
    Female
    Use scleral lenses or PROSE
    Yes
    Eye Condition(s)
    • Dry eye disease
    • Aqueous deficient dry eye
    • Evaporative dry eye
    • Other
    Systemic diseases/conditions related to eye issues
    • CPAP user
    Rated 5 out of 5
    Review posted

    Refresh MEGA-3 Optive

    I have been using these drops every night. They are somewhat thicker than Refresh Plus which I use during the day.

    Loading...
    Effectiveness
    Rated 5 out of 5
    Ease of Use
    Rated 5 out of 5
    Value
    Rated 5 out of 5
    Was this helpful?