{"id":547508912171,"title":"Refresh Optive MEGA-3 (30 PF vials)","handle":"refresh-optive-mega-3","description":"\u003ch1\u003eAbout Refresh Optive MEGA-3\u003cbr\u003e\n\u003c\/h1\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003eActive ingredients: Carboxymethylcellulose, glycerin, polysorbate 80\u003c\/li\u003e\n\u003cli\u003eAlso contains castor oil and flaxseed oil\u003c\/li\u003e\n\u003cli\u003ePreservative-free\u003c\/li\u003e\n\u003cli\u003eBox of 30 0.4mL vials\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch1\u003eDescription (by Rebecca)\u003c\/h1\u003e\n\u003c\/div\u003e\n\u003cp\u003eThis is the latest in the Refresh - slash - Optive branded line. First we had \u003ca href=\"https:\/\/dryeyeshop.com\/products\/refresh-optive\"\u003eOptive\u003c\/a\u003e (actives: glycerin and carboxymethylcellulose), then \u003ca href=\"https:\/\/dryeyeshop.com\/products\/refresh-optive-advanced\"\u003eOptive Advanced\u003c\/a\u003e (those, plus polysorbate 80), and now Optive MEGA-3 (all of the above plus flaxseed and castor oils, tucked quietly into the inactive ingredients list like all lipids. I will leave all discussion of fancy schmancy ingredients like trehalose to the manufacturer (below).\u003c\/p\u003e\n\u003cdiv\u003eThe trend in artificial tears in general for several years now has been to offer a variant with a lipid, now that the dry eye world is gradually becoming so much more meibomian gland savvy. I must say, Dr Holly was way, way ahead of that trend, with \u003ca href=\"https:\/\/dryeyeshop.com\/products\/freshkote\"\u003eFreshKote\u003c\/a\u003e (which I was using, albeit under a different name, more than 15 years ago). And some of you will remember Refresh Endura which had castor oil but was discontinued some years back. Then came Soothe XP, \u003ca href=\"https:\/\/dryeyeshop.com\/products\/systane-balance\"\u003eSystane Balance\u003c\/a\u003e, \u003ca href=\"https:\/\/dryeyeshop.com\/products\/retaine-mgd\"\u003eRetaine MGD\u003c\/a\u003e and so on. \u003c\/div\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cp\u003eRefresh Optive MEGA-3 is quite new and I've had very little feedback on it though I'm quite prepared for the usual I-love-it and I-hate-it. Bottom line is, if you need to try something new and want something with lipids, might be worth a whirl.\u003c\/p\u003e\n\u003cp\u003eIt's rather amusing to me that the manufacturer takes a dig at Retaine MGD in their description. If someone finds a drop that works for them, are they actually going to care that they have to waste a millisecond shaking the tube before opening it? Ah well.\u003c\/p\u003e\n\u003ch1\u003eDescription (from the manufacturer's literature)\u003c\/h1\u003e\n\u003cdiv\u003e\n\u003cp\u003eOur most advanced formula – REFRESH OPTIVE® Mega-3.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePreservative-free, low blur formula fortifies and restores the lipid layer. Its unique blend of natural oils helps prevent tear evaporation.\u003c\/li\u003e\n\u003cli\u003eTreats Dry Eye signs and symptoms associated with Meibomian Gland Dysfunction (MGD).\u003c\/li\u003e\n\u003cli\u003eNourishes all three layers of the tear film damaged by Dry Eye for immediate, long-lasting relief.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis lipid-enhanced lubricant eye drop is clinically proven to treat the signs and symptoms of Dry Eye. Mega-3 does not require shaking prior to use, unlike Retaine® MGD.\u003c\/p\u003e\n\u003cp\u003eREFRESH OPTIVE® Mega-3 Preservative-Free Lubricant Eye Drops come in sterile, single-use vials you can take with you anywhere and are safe to use as often as needed.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eIt is the only artificial tear that delivers a blend of flaxseed and castor oils to the tear film, in a stable nano-emulsion formula.\u003c\/li\u003e\n\u003cli\u003eNano-emulsion technology delivers flaxseed and castor oil, fortifying the lipid layer and helping prevent tear evaporation without compromising patient comfort.\u003c\/li\u003e\n\u003cli\u003ePolysorbate 80 keeps the nano-emulsion from separating, providing consistent stability—no shaking required.\u003c\/li\u003e\n\u003cli\u003eCMC, a water-loving polymer, binds to epithelial cellsto maintain moisture on the ocular surface for rapid on-eye comfort and long-lasting relief.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAll OPTIVE® formulas include the patented osmoprotectant property that comes from the three compatible solutes—glycerin, l-carnitine and erythritol—all of which deliver added protection to the corneal epithelial cells against hypertonic stress.\u003c\/p\u003e\n\u003cp\u003eMEGA-3 contains a fourth osmoprotectant, trehalose, for an advanced approach to treating Dry Eye symptoms. \u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eDrug Facts (from manufacturer's site):\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\nCarboxymethylcellulose sodium 0.5% (eye lubricant)\u003c\/div\u003e\n\u003cdiv\u003eGlycerin 1% (eye lubricant)\u003c\/div\u003e\n\u003cdiv\u003ePolysorbate 80 0.5% (eye lubricant)\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eUses\u003c\/h4\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003eFor the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun.\u003c\/li\u003e\n\u003cli\u003eMay be used as a protectant against further irritation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eWarnings \u003c\/h3\u003e\n\u003ch4\u003eFor external use only.\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003eTo avoid contamination, do not touch tip of container to any surface. Do not reuse. Once opened, discard.\u003c\/li\u003e\n\u003cli\u003eDo not touch unit-dose tip to eye. \u003c\/li\u003e\n\u003cli\u003eIf solution changes color, do not use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eStop use and ask a doctor if\u003c\/b\u003e you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours.\u003c\/p\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cb\u003eKeep out of reach of children. \u003c\/b\u003eIf swallowed, get medical help or contact a Poison Control Center right away.\u003c\/p\u003e\n\u003ch2\u003eDirections\u003c\/h2\u003e\n\u003cp\u003eTo open, TWIST AND PULL TAB TO REMOVE. Instill 1 or 2 drops in the affected eye(s) as needed and discard container.\u003c\/p\u003e\n\u003ch3\u003eOther Information\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003eUse only if single-use container is intact.\u003c\/li\u003e\n\u003cli\u003eUse before expiration date marked on container.\u003c\/li\u003e\n\u003cli\u003eStore at 59°-86°F (15°-30°C).\u003c\/li\u003e\n\u003cli\u003eStore vials in the pouch until use.\u003c\/li\u003e\n\u003cli\u003eRETAIN THIS CART FOR FUTURE REFERENCE.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch4\u003eInactive Ingredients\u003c\/h4\u003e\n\u003cdiv\u003eBORIC ACID; BUTYLATED HYDROXYL TOLUENE; CASTOR OIL; ERYTHRITOL; FLAXSEED OIL; LEVOCARNITINE; PEMULEN TR-2; POLYOXYL 40 STEARATE; PURIFIED WATER; TREHALOSE. MAY CONTAIN SODIUM HYDROXIDE AND\/OR HYDROCHLORIC ACID TO ADJUST PH.\u003c\/div\u003e\n\u003c\/div\u003e","published_at":"2017-12-10T13:31:43-08:00","created_at":"2017-12-10T13:31:43-08:00","vendor":"Allergan","type":"Lubricants","tags":["All","Carboxymethylcellulose sodium","DES","Drop","eye drops","Flaxseed oil","Glycerin","Lube","PF-Vial","PF-Vials","Polysorbate 80","preservative free eyedrops","Refresh (Allergan)","Trehalose","Unit dose vial (preservative free)"],"price":2175,"price_min":2175,"price_max":2175,"available":true,"price_varies":false,"compare_at_price":null,"compare_at_price_min":0,"compare_at_price_max":0,"compare_at_price_varies":false,"variants":[{"id":6741767618603,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"ALL 95773","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Refresh Optive MEGA-3 (30 PF vials)","public_title":null,"options":["Default Title"],"price":2175,"weight":65,"compare_at_price":null,"inventory_quantity":49,"inventory_management":"shopify","inventory_policy":"continue","barcode":"300235773305","requires_selling_plan":false,"selling_plan_allocations":[{"price_adjustments":[{"position":1,"price":2066}],"price":2066,"compare_at_price":2175,"per_delivery_price":2066,"selling_plan_id":1970176043,"selling_plan_group_id":"be5676770f7a2a402f39044871b9ae3b86c22e15"},{"price_adjustments":[{"position":1,"price":2066}],"price":2066,"compare_at_price":2175,"per_delivery_price":2066,"selling_plan_id":1970208811,"selling_plan_group_id":"be5676770f7a2a402f39044871b9ae3b86c22e15"},{"price_adjustments":[{"position":1,"price":2066}],"price":2066,"compare_at_price":2175,"per_delivery_price":2066,"selling_plan_id":1970241579,"selling_plan_group_id":"be5676770f7a2a402f39044871b9ae3b86c22e15"}]}],"images":["\/\/dryeyeshop.com\/cdn\/shop\/products\/Lubricants_Refresh_Optive_Mega3_large_6acde463-6da4-437b-8658-ed2c48eefbac.png?v=1527360117"],"featured_image":"\/\/dryeyeshop.com\/cdn\/shop\/products\/Lubricants_Refresh_Optive_Mega3_large_6acde463-6da4-437b-8658-ed2c48eefbac.png?v=1527360117","options":["Title"],"media":[{"alt":"Refresh Optive MEGA-3 (30 PF vials) - DryEyeShop","id":683089264683,"position":1,"preview_image":{"aspect_ratio":1.333,"height":525,"width":700,"src":"\/\/dryeyeshop.com\/cdn\/shop\/products\/Lubricants_Refresh_Optive_Mega3_large_6acde463-6da4-437b-8658-ed2c48eefbac.png?v=1527360117"},"aspect_ratio":1.333,"height":525,"media_type":"image","src":"\/\/dryeyeshop.com\/cdn\/shop\/products\/Lubricants_Refresh_Optive_Mega3_large_6acde463-6da4-437b-8658-ed2c48eefbac.png?v=1527360117","width":700}],"requires_selling_plan":false,"selling_plan_groups":[{"id":"be5676770f7a2a402f39044871b9ae3b86c22e15","name":"Subscribe and save","options":[{"name":"Delivery frequency","position":1,"values":["Every month","Every 2 months","Every 3 months"]}],"selling_plans":[{"id":1970176043,"name":"Every month","description":null,"options":[{"name":"Delivery frequency","position":1,"value":"Every month"}],"recurring_deliveries":true,"price_adjustments":[{"order_count":null,"position":1,"value_type":"percentage","value":5}],"checkout_charge":{"value_type":"percentage","value":100}},{"id":1970208811,"name":"Every 2 months","description":null,"options":[{"name":"Delivery frequency","position":1,"value":"Every 2 months"}],"recurring_deliveries":true,"price_adjustments":[{"order_count":null,"position":1,"value_type":"percentage","value":5}],"checkout_charge":{"value_type":"percentage","value":100}},{"id":1970241579,"name":"Every 3 months","description":null,"options":[{"name":"Delivery frequency","position":1,"value":"Every 3 months"}],"recurring_deliveries":true,"price_adjustments":[{"order_count":null,"position":1,"value_type":"percentage","value":5}],"checkout_charge":{"value_type":"percentage","value":100}}],"app_id":"43192"}],"content":"\u003ch1\u003eAbout Refresh Optive MEGA-3\u003cbr\u003e\n\u003c\/h1\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003eActive ingredients: Carboxymethylcellulose, glycerin, polysorbate 80\u003c\/li\u003e\n\u003cli\u003eAlso contains castor oil and flaxseed oil\u003c\/li\u003e\n\u003cli\u003ePreservative-free\u003c\/li\u003e\n\u003cli\u003eBox of 30 0.4mL vials\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch1\u003eDescription (by Rebecca)\u003c\/h1\u003e\n\u003c\/div\u003e\n\u003cp\u003eThis is the latest in the Refresh - slash - Optive branded line. First we had \u003ca href=\"https:\/\/dryeyeshop.com\/products\/refresh-optive\"\u003eOptive\u003c\/a\u003e (actives: glycerin and carboxymethylcellulose), then \u003ca href=\"https:\/\/dryeyeshop.com\/products\/refresh-optive-advanced\"\u003eOptive Advanced\u003c\/a\u003e (those, plus polysorbate 80), and now Optive MEGA-3 (all of the above plus flaxseed and castor oils, tucked quietly into the inactive ingredients list like all lipids. I will leave all discussion of fancy schmancy ingredients like trehalose to the manufacturer (below).\u003c\/p\u003e\n\u003cdiv\u003eThe trend in artificial tears in general for several years now has been to offer a variant with a lipid, now that the dry eye world is gradually becoming so much more meibomian gland savvy. I must say, Dr Holly was way, way ahead of that trend, with \u003ca href=\"https:\/\/dryeyeshop.com\/products\/freshkote\"\u003eFreshKote\u003c\/a\u003e (which I was using, albeit under a different name, more than 15 years ago). And some of you will remember Refresh Endura which had castor oil but was discontinued some years back. Then came Soothe XP, \u003ca href=\"https:\/\/dryeyeshop.com\/products\/systane-balance\"\u003eSystane Balance\u003c\/a\u003e, \u003ca href=\"https:\/\/dryeyeshop.com\/products\/retaine-mgd\"\u003eRetaine MGD\u003c\/a\u003e and so on. \u003c\/div\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cp\u003eRefresh Optive MEGA-3 is quite new and I've had very little feedback on it though I'm quite prepared for the usual I-love-it and I-hate-it. Bottom line is, if you need to try something new and want something with lipids, might be worth a whirl.\u003c\/p\u003e\n\u003cp\u003eIt's rather amusing to me that the manufacturer takes a dig at Retaine MGD in their description. If someone finds a drop that works for them, are they actually going to care that they have to waste a millisecond shaking the tube before opening it? Ah well.\u003c\/p\u003e\n\u003ch1\u003eDescription (from the manufacturer's literature)\u003c\/h1\u003e\n\u003cdiv\u003e\n\u003cp\u003eOur most advanced formula – REFRESH OPTIVE® Mega-3.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePreservative-free, low blur formula fortifies and restores the lipid layer. Its unique blend of natural oils helps prevent tear evaporation.\u003c\/li\u003e\n\u003cli\u003eTreats Dry Eye signs and symptoms associated with Meibomian Gland Dysfunction (MGD).\u003c\/li\u003e\n\u003cli\u003eNourishes all three layers of the tear film damaged by Dry Eye for immediate, long-lasting relief.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis lipid-enhanced lubricant eye drop is clinically proven to treat the signs and symptoms of Dry Eye. Mega-3 does not require shaking prior to use, unlike Retaine® MGD.\u003c\/p\u003e\n\u003cp\u003eREFRESH OPTIVE® Mega-3 Preservative-Free Lubricant Eye Drops come in sterile, single-use vials you can take with you anywhere and are safe to use as often as needed.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eIt is the only artificial tear that delivers a blend of flaxseed and castor oils to the tear film, in a stable nano-emulsion formula.\u003c\/li\u003e\n\u003cli\u003eNano-emulsion technology delivers flaxseed and castor oil, fortifying the lipid layer and helping prevent tear evaporation without compromising patient comfort.\u003c\/li\u003e\n\u003cli\u003ePolysorbate 80 keeps the nano-emulsion from separating, providing consistent stability—no shaking required.\u003c\/li\u003e\n\u003cli\u003eCMC, a water-loving polymer, binds to epithelial cellsto maintain moisture on the ocular surface for rapid on-eye comfort and long-lasting relief.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAll OPTIVE® formulas include the patented osmoprotectant property that comes from the three compatible solutes—glycerin, l-carnitine and erythritol—all of which deliver added protection to the corneal epithelial cells against hypertonic stress.\u003c\/p\u003e\n\u003cp\u003eMEGA-3 contains a fourth osmoprotectant, trehalose, for an advanced approach to treating Dry Eye symptoms. \u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eDrug Facts (from manufacturer's site):\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\nCarboxymethylcellulose sodium 0.5% (eye lubricant)\u003c\/div\u003e\n\u003cdiv\u003eGlycerin 1% (eye lubricant)\u003c\/div\u003e\n\u003cdiv\u003ePolysorbate 80 0.5% (eye lubricant)\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eUses\u003c\/h4\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003eFor the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun.\u003c\/li\u003e\n\u003cli\u003eMay be used as a protectant against further irritation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eWarnings \u003c\/h3\u003e\n\u003ch4\u003eFor external use only.\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003eTo avoid contamination, do not touch tip of container to any surface. Do not reuse. Once opened, discard.\u003c\/li\u003e\n\u003cli\u003eDo not touch unit-dose tip to eye. \u003c\/li\u003e\n\u003cli\u003eIf solution changes color, do not use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eStop use and ask a doctor if\u003c\/b\u003e you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours.\u003c\/p\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cb\u003eKeep out of reach of children. \u003c\/b\u003eIf swallowed, get medical help or contact a Poison Control Center right away.\u003c\/p\u003e\n\u003ch2\u003eDirections\u003c\/h2\u003e\n\u003cp\u003eTo open, TWIST AND PULL TAB TO REMOVE. Instill 1 or 2 drops in the affected eye(s) as needed and discard container.\u003c\/p\u003e\n\u003ch3\u003eOther Information\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003eUse only if single-use container is intact.\u003c\/li\u003e\n\u003cli\u003eUse before expiration date marked on container.\u003c\/li\u003e\n\u003cli\u003eStore at 59°-86°F (15°-30°C).\u003c\/li\u003e\n\u003cli\u003eStore vials in the pouch until use.\u003c\/li\u003e\n\u003cli\u003eRETAIN THIS CART FOR FUTURE REFERENCE.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch4\u003eInactive Ingredients\u003c\/h4\u003e\n\u003cdiv\u003eBORIC ACID; BUTYLATED HYDROXYL TOLUENE; CASTOR OIL; ERYTHRITOL; FLAXSEED OIL; LEVOCARNITINE; PEMULEN TR-2; POLYOXYL 40 STEARATE; PURIFIED WATER; TREHALOSE. MAY CONTAIN SODIUM HYDROXIDE AND\/OR HYDROCHLORIC ACID TO ADJUST PH.\u003c\/div\u003e\n\u003c\/div\u003e"}