Ingredient guide for OTC lubricant eye drops, gels and ointments

Active and inactive ingredients for lubricant eye drops, gels and ointments

Updated on
Ingredient guide for OTC lubricant eye drops, gels and ointments

Source: DailyMed (National Library of Medicine drug label database)

 Product
Active ingredients
Inactive ingredients (preservatives highlighted)

Bion Tears (30 PF vials)

Dextran 70 0.1%, Hypromellose 2910 0.3%

Calcium chloride, magnesium chloride, potassium chloride, purified water, sodium bicarbonate, sodium chloride, zinc chloride, hydrochloric acid and/or sodium hydroxide and/or carbon dioxide to adjust pH.

BioTrue Hydration Boost (10mL PF bottle)

Glycerin 0.5%

boric acid, erythritol, potassium chloride, purified water, sodium borate, sodium hyaluronate

BioTrue Hydration Boost
PF vials

Glycerin 0.5%

boric acid, erythritol, potassium chloride, purified water, sodium borate, sodium hyaluronate

Blink Boost

Glycerin 0.5%

boric acid, erythritol, potassium chloride, purified water, sodium borate, sodium hyaluronate

Blink GelTears

Polyethylene Glycol 400 0.25%

Boric Acid; Calcium Chloride; Magnesium Chloride;Potassium Chloride; Purified Water; Sodium Borate; Sodium Chloride; Sodium Chlorite (OcuPure brand) as a preservative; Sodium Hyaluronate.

Blink Nourish

Discontinued 4Q2025


Blink Tears

Polyethylene Glycol 400 0.25%

Boric Acid; Calcium Chloride; Magnesium Chloride; Potassium Chloride; Purified Water; Sodium Borate; Sodium Chloride; Sodium Chlorite (OcuPure Brand) as a Preservative; Sodium Hyaluronate.

Blink Tears PF

Discontinued 1Q2026


Blink Triple Care

Polyethylene Glycol 400 0.25%

Boric acid, castor oil, PEG 40 hydrogenated castor oil, potassium chloride, purified water, sodium borate, sodium chloride, sodium chlorite (OcuPure brand) as preservative, sodium hyaluronate

Blink Triple Care PF

Polyethylene Glycol 400 0.25%

Boric acid, castor oil, polyoxyl-40 hydrogenated castor oil. potassium chloride, purified water, sodium borate, sodium chloride, sodium hyaluronate.

Clear Eyes Natural Tears 

Polyvinyl alcohol 0.5%

Povidone 0.6%

Benzalkonium Chloride, Dextose, Edetate Disodium, Potassium Chloride, Purified Water, Sodium Bicarbonate, Sodium Chloride, Sodium Citrate, Sodium Phosphate (mono- and dibasic)

Clear Eyes Outdoor Dry Eye Protection

Polyvinyl alcohol 0.5%

Povidone 0.6%

Benzalkonium Chloride, Dextose, Edetate Disodium, Potassium Chloride, Purified Water, Sodium Bicarbonate, Sodium Chloride, Sodium Citrate, Sodium Phosphate (mono- and dibasic)

Eyeganics Organic Tears

Glycerin 0.2% (certified organic)

Sodium chloride, water

Eyeleve

Light mineral oil 0.5%

Mineral oil 0.5%

Cetalkonium Chloride, Glycerol, Poloxamer 188, Tris Hydrochloride, Tromethamine, Tyloxapol, Water for Injection

Freshkote Preservative Free 

RECALL IN EFFECT

Polyvinyl pyrrolidone 2.0%, Polyvinyl alcohol 2.7%

Boric acid, Edetate disodium, Ethanol, Glycerin, Lecithin, Phospholipids, Polysorbate-80, Potassium chloride, Purified water, Sodium chloride. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Genteal Gel (Severe)

RECALL IN EFFECT

Hypromellose 0.3%.

carbopol 980, phosphoric acid, purifed water, sodium hydroxide, sodium perborate, and sorbitol

Genteal Moderate

Dextran 70 0.1%, Glycerin 0.2%, Hypromellose 0.3%

Boric acid, calcium chloride, glycine, hydrochloric acid and/or sodium hydroxide (to adjust pH), magnesium chloride, POLYQUAD® (polyquaternium-1) 0.001% preservative, polysorbate 80, potassium chloride, purified water, sodium chloride, zinc chloride.

Genteal ointment

White petrolatum 93%

Mineral oil 4%

anhydrous liquid lanolin

Genteal Tears PF

Dextran 70 0.1%, Hypromellose 2910 0.3%

Potassium Chloride, Purified Water, Sodium Borate, Sodium Chloride, May contain: Hydrochloric Acid, Sodium Hydroxide

Genteal Tears Gel Drops

Polyethylene glycol 400 0.4%
Propylene glycol 0.3%

Aminomethylpropanol, Boric Acid, Edetate Disodium, Hydroxypropyl Guar, Polyquad® (Polyquaternium-1) 0.001% Preservative, Potassium Chloride, Sodium Chloride, Sorbitol And Purified Water. May Contain Hydrochloric Acid And/Or Sodium Hydroxide To Adjust Ph

Ivizia Lubricant Eye Drops (PF bottle)

Povidone 0.5%

Hydrochloric acid, purified water, sodium chloride, sodium hyaluronate, trehalose, tromethamine

Ivizia Lubricant Eye Gel (PF vials)

Povidone 0.5%

Carbomer, purified water, sodium hyaluronate, sodium hydroxide, sorbital, trehalose

Oasis Tears

Glycerin 0.22%

EDTA, potassium sorbate, sodium chloride, sodium hyaluronate, sodium hydroxide, sodium phosphate dibasic, sodium phosphate monobasic, water

Oasis Tears (PF vials)

Glycerin 0.22%

Hyaluronan, sodium chloride, sodium phosphate dibasic, sodium phosphate monobasic, water.

Oasis Tears (PF bottle)

Glycerin 0.25%

sodium chloride, sodium hyaluronate, sodium hydroxide, sodium phosphate dibasic, sodium phosphate monobasic, water

Oasis Tears Plus (PF vials)

Glycerin 0.22%

Hyaluronan, sodium chloride, sodium phosphate dibasic, sodium phosphate monobasic, water.

Oasis Tears Plus (PF bottle)

Glycerin 0.25%

sodium chloride, sodium hyaluronate, sodium hydroxide, sodium phosphate dibasic, sodium phosphate monobasic, water

Optase Allegro (PF bottle)

Hydroxyethyl Cellulose 0.35%

Citric acid, ectoin, purified water, sodium chloride, trisodium citrate dihydrate

Optase Dry Eye Intense Drops (PF bottle, PF vials)

Glycerin 0.2%

Hydrochloric acid, sodium hyaluronate, sorbital, trometamol, water

Optase Dry Eye Spray

Glycerin 1%

Sea buckthorn seed oil, sodium hyaluronate, trometamol-citrate

Optase Hylo Forte (PF bottle)

Glycerin 0.3%

Borax, Boric Acid, Citric Acid anhydrous, Sodium Chloride, Sodium Citrate Dihydrate, Sodium Hyaluronate, Water

Optase Hylo Night

White Petrolatum 90%, lanolin 6.9%

Retinol palmitate (Vitamin A), light liquid paraffin
May contain peanut oil

Optase Hylo Relief (PF bottle)

Glycerin 0.25%

Borax, Boric Acid, Citric Acid anhydrous, Sodium Chlroide, Sodium Citrate Diydrate, Sodium Hyaluronate, Water

Optase MGD Advanced (PF bottle)

Glycerin 0.9%

Citric acid monohydrate, Polyoxyethylenesorbitan, Monooleate, Potassium Chloride, Purified Water, Sacha Inchi Seed Oil, Sodium hyaluronate, Sodium Monooleate, Trehalose, Tromethamine

Refresh Celluvisc (PF vials)

Carboxymethylcellulose sodium 1%

Calcium chloride, potassium chloride, purified water, sodium chloride, and sodium lactate.

Refresh Classic (PF vials)

Polyvinyl Alcohol

1.4% Povidone 0.6%

Purified water, sodium chloride. May also contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Refresh Digital

Carboxymethylcellulose sodium 0.5%

Glycerin 1%

Polysorbate 80 0.5%

Boric acid; carbomer copolymer type A; castor oil; erythritol; levocarnitine; purified water; PURITE® (stabilized oxychloro complex); and sodium hydroxide.

Refresh Digital (PF vials)

Carboxymethylcellulose sodium 0.5%

Glycerin 1%

Polysorbate 80 0.5%

Boric acid; carbomer copolymer type A; castor oil; erythritol; levocarnitine; purified water; and sodium hydroxide.

Refresh LacriLube

Mineral Oil 42.5%

White Petrolatum 56.8%

Chlorobutanol and lanolin alcohols.

Refresh Liquigel

Carboxymethylcellulose sodium 1%

Boric acid, calcium chloride, magnesium chloride, potassium chloride, purified water, PURITE® (stabilized oxychloro complex), sodium borate, and sodium chloride.

Refresh Optive

Carboxymethylcellulose sodium 0.5%

Glycerin 0.9%

Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; PURITE ® (stabilized oxychloro complex); sodium borate decahydrate; and sodium citrate dihydrate.

Refresh Optive (PF vials)

Carboxymethylcellulose sodium 0.5%

Glycerin 0.9%

Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium borate decahydrate; and sodium citrate dihydrate.

Refresh Optive Advanced

Carboxymethylcellulose sodium 0.5%
Glycerin 1%
Polysorbate 80 0.5%

Boric acid; castor oil; erythritol; levocarnitine; carbomer copolymer type A; purified water; and PURITE ® (stabilized oxychloro complex) May also contain sodium hydroxide to adjust pH.

Refresh Optive Advanced (PF vials)

Carboxymethylcellulose sodium 0.5%
Glycerin 1%
Polysorbate 80 0.5%

Boric acid; carbomer copolymer type A; castor oil; erythritol; levocarnitine; purified water; and sodium hydroxide.

Refresh Optive Gel Drops

Carboxymethylcellulose sodium 1%

Glycerin 0.9%

Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; PURITE® (stabilized oxychloro complex); sodium borate decahydrate; sodium citrate dihydrate; purified water.

Refresh Optive MEGA-3 (PF vials)

Carboxymethylcellulose sodium 0.5%

Glycerin 1%

Polysorbate 80 0.5%

Boric acid; butylated hydroxyl toluene; castor oil; erythritol; flaxseed oil; levocarnitine; pemulen TR-2; polyoxyl 40 stearate; purified water; sodium hydroxide; trehalose.

Refresh Optive MEGA-3 (PF bottle)

Carboxymethylcellulose sodium 0.5%

Glycerin 1%

Polysorbate 80 0.5%

Boric acid; butylated hydroxyl toluene; castor oil; erythritol; flaxseed oil; levocarnitine; pemulen TR-3; polyoxyl 40 stearate; purified water; trehalose. May contain sodium hydroxide and/or hydrochloric acid to adjust pH.

Refresh Plus (PF vials)

Carboxymethylcellulose sodium 0.5%

Calcium chloride; magnesium chloride; potassium chloride; purified water; sodium chloride; and sodium lactate. May also contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Refresh PM ointment

Mineral Oil 42.5%

White Petrolatum 57.3%

Lanolin alcohols

Refresh Relieva

carboxymethylcellulose sodium 0.5%
glycerin 0.9%

Boric acid; calcium chloride dihydrate; erythritol; magnesium chloride hexahydrate; potassium chloride; purified water; PURITE ® (stabilized oxychloro complex); sodium borate decahydrate; sodium citrate dihydrate; and sodium hyaluronate. May contain hydrochloric acid and/or sodium hydroxide (to adjust pH).

Refresh Relieva (PF vials or PF bottle)

carboxymethylcellulose sodium 0.5%
glycerin 0.9%

Boric acid; calcium chloride dihydrate; erythitrol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium borate decahydrate; sodium citrate dihydrate; and sodium hyaluronate. May also contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Refresh Relieva PF Xtra (PF bottle)

carboxymethylcellulose sodium 0.5%
glycerin 0.9%

Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium borate decahydrate; sodium citrate dihydrate; sodium hyaluronate; and trehalose. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Refresh Tears

Carboxymethylcellulose Sodium 0.5%

Oxychloro complex, Sodium Borate decahydrate, Sodium chloride, Potassium chloride, Calcium chloride dihydrate, Magnesium chloride hexahydrate, Boric acid, Sodium hydroxide to adjust pH and Purified water.

Refresh Tears PF (PF bottle)

Carboxymethylcellulose Sodium 0.5%

Glycerin 0.9%

Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium borate decahydrate; and sodium citrate dihydrate.

Retaine MGD (PF vials)

Light mineral oil 0.5%

Mineral oil 0.5%

Cetrimonium bromide, glycerol, poloxamer 188, tris hydrochloride, tromethamine, tyloxapol, water for injection.

Retaine PM ointment

Mineral oil 20%

White petrolatum 80%

n/a

Rohto Dry Aid

Povidone 0.68%

Propylene glycol 0.3%

Boric acid, calcium chloride, edetate disodium, magnesium sulfate, menthol, PEG010 castor oil, poloxamer, polyaminopropyl biguanide, polyoxyl stearate, purified water, sesame oil, sodium borate.

Soothe Long Lasting Hydration

Povidone 2.0%

benzalkonium chloride (0.005%), boric acid, edetate disodiumdihydrate, purified water, sodium borate, sodium chloride, tyloxapol. Hydrochloric acid and/or sodium hydroxide may be used to adjust pH.

Soothe Lubricant Eye Drops Hydration

Povidone 1.25%

boric acid, potassium chloride, sodium borate and sodium chloride; preserved with edetate disodium 0.1% and sorbic acid 0.1%

Soothe Lubricant Eye Drops (PF vials)

Glycerin 0.6% Propylene Glycol 0.6%

boric acid, hydroxyalkylphosphonate, purified water, sodium alginate, sodium borate

Soothe Maximum Hydration

Povidone 2.0%

benzalkonium chloride (0.005%), boric acid, edetate disodiumdihydrate, purified water, sodium borate, sodium chloride, tyloxapol. Hydrochloric acid and/or sodium hydroxide may be used to adjust pH.

Soothe Night Time Ointment

Mineral oil 20%

White petrolatum 80%

n/a

Soothe XP Emollient 

Light mineral oil 1.0%

Mineral oil 4.5%

boric acid, edetate disodium, octoxynol-40, polyquaternium-1 (preservative), polysorbate 80, purified water, sodium borate decahydrate. May contain hydrochloric acid and/or sodium hydroxide (to adjust pH).

Soothe XP Emollient (PF vials)

Discontinued 3Q2025


Systane

Polyethylene Glycol 400 0.4%,

Propylene Glycol 0.3%

Boric acid, calcium chloride, hydroxypropyl guar, magnesium chloride, polyquaternium-1 as a preservative, potassium chloride, purified water, sodium chloride, zinc chloride. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Systane (PF vials)

Polyethylene Glycol 400 0.4%,

Propylene Glycol 0.3%

Boric acid, calcium chloride, hydroxypropyl guar, magnesium chloride, potassium chloride, purified water, sodium chloride, zinc chloride. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Systane Balance

Propylene Glycol 0.6%

Boric acid, dimyristoyl phosphatidylglycerol, edetate disodium, hydroxypropyl guar, mineral oil, polyoxyl 40 stearate, POLYQUAD® (polyquaternium-1) 0.001% preservative, sorbitan tristearate, sorbitol and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Systane Complete

Propylene Glycol 0.6%

Boric acid, dimyristoyl phosphatidylglycerol, edetate disodium, hydroxypropyl guar, mineral oil, polyoxl 40 Stearate, POLYQUAD (polyquaternium-1) 0.001% preservative, sorbitan tristearate, sorbital and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Systane Complete (PF vials)

Propylene Glycol 0.6%

Boric acid, dimyristoyl phosphatidylglycerol, hydroxypropyl guar mineral oil, polyoxl 40 stearate, sorbitan tristearate, sorbital and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Systane Gel Drops

Polyethylene Glycol 400 0.4%

Propylene Glycol 0.3%

Aminomethylpropanol, boric acid, edetate disodium, hydroxypropyl guar, POLYQUAD® (polyquaternium-1) 0.001% preservative, potassium chloride, sodium chloride, sorbitol and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Systane Hydration (PF vials or PF bottle)

Polyethylene Glycol 400 0.4%

Propylene Glycol 0.3%

aminomethylpropanol, boric acid, hydroxypropyl guar, potassium chloride, purified water, sodium borate, sodium chloride, sodium hyaluronate, sorbitol. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Systane Lubricant Eye Gel

SUBJECT TO RECALL

Hypromellose 0.3%

Carbopol 980, phosphonic acid, purified water, sodium perborate and sorbitol. May contain sodium hydroxide to adjust pH.

Systane Nighttime ointment

White petrolatum 94%

Mineral oil 3%

Anhydrous Liquid Lanolin 3%

Systane Pro PF (PF bottle)

Propylene glycol 0.6%

Boric acid, dimyristoyl prosphatidylglycerol, hydroxypropyl guar, mineral oil, polyoxyl 40 stearate, sodium hyaluronate, sorbitan tristearate, sorbitol, purified water.

Systane Ultra

Polyethylene Glycol 400 0.4%

Propylene Glycol 0.3%

Aminomethylpropanol, boric acid, hydroxypropyl guar, POLYQUAD* (polyquaternium-1) 0.001% preservative, potassium chloride, purified water, sodium chloride, sorbitol. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Systane Ultra (PF vials or PF bottle)

Polyethylene Glycol 400 0.4%

Propylene Glycol 0.3%

Aminomethylpropanol, boric acid, hydroxypropyl guar, potassium chloride, purified water, sodium chloride, sorbitol. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

TheraTears Dry Eye Therapy

Sodium Carboxymethyl Cellulose 0.25%

Borate Buffers, Calcium Chloride, Dequest, Magnesium Chloride, Potassium Chloride, Purified Water, Sodium Bicarbonate, Sodium Chloride, Sodium Perborate, Sodium Phosphate

TheraTears Dry Eye Therapy (PF vials)

Sodium Carboxymethyl Cellulose 0.25%

Borate Buffers, Calcium Chloride, Magnesium Chloride, Potassium Chloride, Purified Water, Sodium Bicarbonate, Sodium Chloride and Sodium Phosphate.

ThearsTears Dry and Tired (PF vials)

Sodium Carboxymethyl Cellulose 0.5%

Calcium chloride, magnesium chloride, potassium chloride, purified water, sodium chloride, sodium lactate. May also contain hydrochloric acid and/or sodium hydroxide to adjust pH.

TheraTears EXTRA 

Sodium Carboxymethyl Cellulose 0.25%

Boric Acid Calcium Chloride, Dequest, Potassium Chloride, Sodium Bicarbonate, Sodium Borate, Sodium Chloride, Magnesium Chloride, Sodium Perborate, Sodium Phosphate Trehalose, Water for Injection

TheraTears Extra (PF vials)

Sodium Carboxymethyl Cellulose 0.25%

Boric acid, calcium chloride, hydrochlorid acid*, magnesium chloride, potassium chloride, sodium bicarbonate, sodium borate, sodium chloride, sodium hydroxide*, sodium phosphate, trehalose and water for injection. *May contain these ingredients to adjust pH.

TheraTears nighttime (gel) (PF vials)

Sodium Carboxymethyl Cellulose 1%

Borate Buffer, Calcium Chloride, Magnesium Chloride, Potassium Chloride, Water (Purified), Sodium Bicarbonate (Baking Soda), Sodium Chloride, Sodium Phosphate

Visine Dry Eye Relief

Polyethylene glycol 400 1%

ascorbic acid, boric acid, dextrose, glycerin, glycine, hypromellose, magnesium chloride, polyquaternium-42, potassium chloride, purified water, sodium borate, sodium chloride, sodium citrate, sodium lactate, sodium phosphate dibasic

Visine Tired Eye Dry Eye Relief

Polyethylene glycol 400 1%

ascorbic acid, boric acid, dextrose, glycine, magnesium chloride, polyquaternium-42, potassium chloride, purified water, sodium borate, sodium chloride, sodium citrate, sodium lactate, sodium phosphate dibasic

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