Last updated: 6/23/2025

Product Recall

On 5/15/25, Contamac Solutions announced a voluntary product recall of six lots of Nutrifill. The reason for the recall was sterility concerns related to customer complaints, which included serious injuries.

Dry Eye Shop recommends against the use of Nutrifill, including units that are not on the recall list.

Please check your supplies in case you have any of these lots, and follow the manufacturer's instructions at this link.

Here is a link to the FDA's official recall record.

What to do if you think you were harmed by Nutrifill

1. Contact your doctor.
2. Report your experience to Contamac at hello@contamacsolutions.com
3. Report your experience to the FDA by filling out a Medwatch report. 

Original blog post (February 2025)

Temporary shortage

Nutrifill is temporarily unavailable. At this time, the manufacturer does not have an estimated back-in-stock date. 

Talk to your provider

If Nutrifill is your normal filling solution, make sure to let your provider know if you're not able to get more and ask for their guidance on substitutions.

Alternative filling solution options

Buffered salines (ScleralFil, Purilens)

Scleralfil

The obvious "most similar" choice is Scleralfil. 

What's the same:

• Type (buffered - pH balanced to match the eye)
• Size (10mL vial)

What's different:

• Cheaper
• Sold in box of 30 (vs Nutrifill which is 35)
• Buffering system: Both products are buffered, meaning they have additives to raise and stabilize the pH. Nutrifill is phosphate-buffered, while Scleralfil is borate-buffered.  
• Ingredients: Other than sodium chloride (salt) and water, Nutrifill contains alcium, magnesium potassium and phosphate, while Scleralfil contains sodium borate and boric acid. These ingredients are also common in artificial tear products.

Purilens

Purilens has the same ingredients as Scleralfil but is packaged differently. It is sold in 2oz and 4oz sizes. The bottles are the "puncture" type, and the bottles must be discarded either within 14 days (per label) or earlier, depending on your doctor's advice. Some prefer their patients not to fill sclerals with Purilens more than 48 hours after the bottle is open, due to potential for contamination. it is a very popular solution for rinsing, however, especially for newer "high utilization" scleral users. 

2oz size is sold in 2packs and 6packs)

4oz size is sold in 3packs, 6packs and 12packs

Click on Purilens to browse all.

Unbuffered salines + PF tears

If you are used to buffered saline, then unbuffered saline (which is acidic) may not be comfortable for you. However, some people with sensitive eyes may not be able to tolerate the borate-buffered salines (Scleralfil and Purilens). In this case, an alternative that has long been popular is to use an unbuffered saline e.g. Lacripure, VibrantVue or Tangible Fill but add one or more drops of a preservative-free artificial tear. Refresh Celluvisc is common as a supplemental filling solution (our last poll indicated that 61% of those who add something to saline are adding Celluvisc).

Fill with PF tears only

Expensive, and only suitable for some users, but definitely an option. Check with your provider.

Economical options for trying different salines

We know it's frustrating to have to buy a full box of a product only to find that it doesn't agree with you. Here are the smallest quantities available of each:

• Purilens 2oz 2pack ($10.95)
• Lacripure 7-vial sample pack ($7.50)
• VibrantVue 6-vial sample pack ($2.50)
• ScleralFil has no sample sizes available, so the cheapest is box of 30 for $19.95.

In terms of artificial tears used for filling, the cheapest preservative-free brand name option that I know of us Refresh Plus 70packs sold at Costco.