Systane Hydration Multidose Preservative-Free - DryEyeShop
Systane Hydration Multidose Preservative-Free - DryEyeShop

SKU: ACL-PN 0065151006

Systane Hydration (10mL MDPF bottle)

Rated 4.6 out of 5
Based on 9 reviews
Regular price
$19.95
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$19.95
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  • Preservative-free
  • Active ingredients: polyethylene glycol, propylene glycol
  • Contains sodium hyaluronate
  • 10mL (0.34 fl oz) preservative-free multi-dose bottle

This is the PF multidose version of Systane Hydration.

Systane Hydration is basically regular Systane plus hyaluronic acid (HA), otherwise known as sodium hyaluronate or (as they are saying) just plain hyaluronate. HA is a good thing, and seeing more and more US companies jump on that bandwagon is a good thing.

We now - finally - have quite a few on the US market. Outside the US, HA is used as the activate ingredient in many very popular drops such as Hylo Forte. However, due to (in my opinion) antiquated FDA regulations, American manufacturers are not allowed to list HA as an active ingredient - which also means they can't advertise it (a/k/a explain its benefits). In addition, the concentration of HA is not listed since it's on the "inactives" list. So annoying.

But as I was saying, they have to list something else as the active ingredient. Each manufacturer has gone down a different path. For Oasis, and for Clear Eyes Pure Relief, it's glycerin. For Refresh Relieva, it's CMC and glycerin, so basically a cross between Refresh Plus and the others. For Blink, it's polyethylene glycol. And now for Systane, it's the usual Systane stuff (PEG and prop glycol).

If you're a Systane fan, I encourage you to try Systane Hydration, since you're already used to the basic ingredients and this would give you the benefit of the HA.

I'm very happy to see more and more preservative-free multi-dose bottles on the US market, though they are still uncommon and there is not a lot of awareness about them. These bottles are more economical than vials as well as more environmentally friendly. The one downside is that they are a little harder to use. For most of us, not a problem, just a matter of getting used to. But for arthritic hands, it can be a more serious problem.

UPDATE June 2021: I'm amazed at how much strongly positive feedback I've had about this drop in the short time since it was launched. 

New SYSTANE® HYDRATION Multi-Dose Preservative-Free eye drops help restore moisture to dry eyes with the soothing relief of HydroBoost technology.

Drug Facts

Active ingredients

Polyethylene Glycol 400 0.4%
Propylene Glycol  0.3%

Uses

For use as a protectant against further irritation or to relieve dryness of the eye.

Warnings

For external use only

Do not use

  • if this product changes color or becomes cloudy
  • if you are sensitive to any ingredient in this product

When using this product

  • do not touch tip of container to any surface to avoid contamination
  • replace cap after each use

Stop use and ask a doctor if you experience any of the following:

  • eye pain
  • changes in vision
  • continued redness or irritation of the eye
  • condition worsens or persists for more than 72 hours

 Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

  • put 1 or 2 drops in the affected eye(s) as needed

Directions for using this bottle:

  • Hold the bottle just below the cap and twist the cap to open.
  • BEFORE FIRST USE, hold the bottle upside down and dispense one drop of product to discard.
  • Shake the bottle downward to remove residual product (see picture on box)
  • Place 1 or 2 drops in the affected eye(s) as needed and blink
  • After use, shake the bottle downward to remove residual product that may be left on the tip (see picture on box).
  • Replace cap after use.

Other information

store at room temperature

Inactive ingredients

aminomethylpropanol, boric acid, hydroxypropyl guar, potassium chloride, purified water, sodium borate, sodium chloride, sodium hyaluronate, sorbitol. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

average rating 4.6 out of 5
Based on 9 reviews
  • 5 Stars
    7 Reviews
  • 4 Stars
    1 Review
  • 3 Stars
    0 Reviews
  • 2 Stars
    1 Review
  • 1 Star
    0 Reviews
89% of reviewers would recommend this product to a friend
Effectiveness
Rated 4 out of 5
Ease of Use
Rated 4 out of 5
Value
Rated 4 out of 5
9 Reviews
Reviewed by Sara M., from United States
Verified Buyer
I recommend this product
Age Range
41 - 50
Use scleral lenses or PROSE
No
Eye Condition(s)
  • Dry eye disease
  • Blepharitis/MGD
Rated 5 out of 5
Review posted

My favorite daytime eye drops!

When I was diagnosed with a dry eye condition, I tried nearly all of the preservative-free eye drops at the drugstore, and felt like most of them did very little for me (or even made things worse). I'd begun to think I'd need something more viscous, like a gel or ointment, all the time. But it turns out my eyes just really love hyaluronic acid, and these drops work well for me, last a while, and are easy to repurchase here or (in a pinch) at a local store. I like being able to use a multidose bottle, and find these clear bottles a little softer than some of the brands that use opaque bottles, though some of these bottles seem more prone to staying "squeezed-in" after use than others. I'd love for more brands to formulate with HA, this has been a game changer for me.

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Effectiveness
Rated 5 out of 5
Ease of Use
Rated 5 out of 5
Value
Rated 5 out of 5
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Reviewed by Francine S., from United States
Verified Buyer
I recommend this product
Age Range
71 - 80
Gender
Female
Use scleral lenses or PROSE
No
Eye Condition(s)
  • Dry eye disease
  • Evaporative dry eye
  • Aqueous deficient dry eye
  • Blepharitis/MGD
Systemic diseases/conditions related to eye issues
  • Other
Rated 5 out of 5
Review posted

My Favorite Drops

I've had severe burning dry eyes for many years, and I've tried dozens of drops. These and Hylo-Forte have worked best for me. I love the thickness and coolness of the Systane Hydration. I don't need to use them as often as I have had to with other drops.

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Effectiveness
Rated 5 out of 5
Ease of Use
Rated 5 out of 5
Value
Rated 5 out of 5
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Reviewed by Kim F., from United States
Verified Buyer
I recommend this product
Age Range
61 - 70
Gender
Male
Use scleral lenses or PROSE
No
Eye Condition(s)
  • Keratoconus or PMD
Rated 5 out of 5
Review posted

These drops are great

I had been using other drops until my contact specialist suggested using Systane. These are much better for my Gas permeable lenses. I use them a few times each day to keep my contacts and eyes moist.

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Effectiveness
Rated 5 out of 5
Ease of Use
Rated 5 out of 5
Value
Rated 5 out of 5
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Reviewed by James, from United States
Verified Buyer
I recommend this product
Age Range
31 - 40
Gender
Male
Use scleral lenses or PROSE
No
Eye Condition(s)
  • Enucleation/Ocular prosthesis wearer
  • Other
Rated 5 out of 5
Review posted

The BEST for Me

I haven't tried EVERY drop out there, but I recently compared these to some other Systane formulas, and the others actually caused unpleasant results. I'm a retinoblastoma survivor who is now on Restasis because my eye no longer produces tears.

These drops are fantastic for me for whatever reason. I'd recommend anyone / everyone give them a try.

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Effectiveness
Rated 5 out of 5
Ease of Use
Rated 5 out of 5
Value
Rated 5 out of 5
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Reviewed by Alice, from United States
I don't recommend this product
Age Range
41 - 50
Gender
Female
Use scleral lenses or PROSE
No
Eye Condition(s)
  • Blepharitis/MGD
  • Evaporative dry eye
  • Dry eye disease
Rated 2 out of 5
Review posted

bottle is tough to use

Drops themselves seemed ok, but using the bottle is confusing. It doesn't have a normal dropper tip and I cannot find clear directions on how to use this weird nipple type bottle top.

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Effectiveness
Rated 3 out of 5
Ease of Use
Rated 1 out of 5
Value
Rated 3 out of 5
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DryEyeShop

This type of bottle is designed to prevent any contamination by way of a small filter. The manufacturer directs to hold the bottle just below the cap and twist open. Before fist use, they advise to hold the bottle upside down and dispense a drop of product to discard. Shake the bottle downward to remove residual product. Place 1 or 2 drops in the affected eye(s) as needed and blink. After use, shake the bottle downward to remove residual product that may be left on the tip, replace cap after use, and store at room temperature. If you have any problems with product not being dispersed, please call our office at 1(877)693-7939.